About   Help   FAQ
Chemically induced Allele Detail
Symbol: Usp14nmf375
Name: ubiquitin specific peptidase 14; neuroscience mutagenesis facility, 375
MGI ID: MGI:3622127
Synonyms: NMF375
Gene: Usp14  Location: Chr18:9993615-10030149 bp, - strand  Genetic Position: Chr18, 4.91 cM
Strain of Origin:  C57BL/6J
Allele Type:    Chemically induced (ENU) (Hypomorph)
Mutation:    Single point mutation
Mutation detailsENU mutagenesis induced a T to C transition in position 4 of the splice site donor region of intron 9. Western blot anlaysis confirmed the absence of protein expression in the spinal cord without the detection of truncated proteins. Authors state that this allele is hypomorphic based on phenotypic analysis.
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Usp14 Mutation:  39 strains or lines available
Original:  J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.17
The Jackson Laboratory