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Lxntm1Yari
Targeted Allele Detail
Nomenclature
Symbol: Lxntm1Yari
Name: latexin; targeted mutation 1, Yasuyoshi Arimatsu
MGI ID: MGI:3622076
Synonyms: Lxn-
Gene: Lxn  Location: Chr3:67365332-67371240 bp, - strand  Genetic Position: Chr3, 30.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:106948
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced the coding sequence in exon 1. Western blot and immunohistochemistry failed to detect protein in mutant brain samples. (J:106948)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lxn Mutation:  5 strains or lines available
References
Original:  J:106948 Jin M, et al., Reduced pain sensitivity in mice lacking latexin, an inhibitor of metallocarboxypeptidases. Brain Res. 2006 Feb 23;1075(1):117-21
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/26/2022
MGI 6.21
The Jackson Laboratory