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Targeted Allele Detail
Symbol: Bmp2tm1.1Jfm
Name: bone morphogenetic protein 2; targeted mutation 1.1, James F Martin
MGI ID: MGI:3620971
Synonyms: Bmp2d, Bmp2null
Gene: Bmp2  Location: Chr2:133552159-133562885 bp, + strand  Genetic Position: Chr2, 65.21 cM
Germline Transmission:  Earliest citation of germline transmission: J:99582
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele is a derivative of Bmp2tm1Jfm in which exon 3 is deleted by Cre-mediated recombination. Mice carrying the Bmp2tm1Jfm allele were mated to Tg(Nes-cre)1Mrt mice (J:58999) and offspring were screened for the heritable deletion. PCR analysis confirmed deletion of exon 3. (J:99582)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp2 Mutation:  15 strains or lines available
Original:  J:99582 Ma L, et al., Generation of a Bmp2 conditional null allele. Genesis. 2005 Jul;42(3):203-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory