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Chmtm1.1Seab
Targeted Allele Detail
Nomenclature
Symbol: Chmtm1.1Seab
Name: choroidermia; targeted mutation 1.1, Miguel C Seabra
MGI ID: MGI:3617903
Synonyms: Chmflox
Gene: Chm  Location: ChrX:113040593-113185517 bp, - strand  Genetic Position: ChrX, 48.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105458
Parent Cell Line:  GSI-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Cre expression in the germline produced these mice in which exon 4 was flanked by loxP sites. (J:105458)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chm Mutation:  9 strains or lines available
References
Original:  J:105458 Tolmachova T, et al., Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia. J Clin Invest. 2006 Feb;116(2):386-94
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory