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Cebpatm1Btp
Targeted Allele Detail
Nomenclature
Symbol: Cebpatm1Btp
Name: CCAAT/enhancer binding protein (C/EBP), alpha; targeted mutation 1, Bo Torben Porse
MGI ID: MGI:3617752
Synonyms: C/EBPalphadeltaPHR
Gene: Cebpa  Location: Chr7:35119293-35121926 bp, + strand  Genetic Position: Chr7, 21.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105554
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsAmino acids 180-194 were removed via homologous recombination. Expression of the mutant was comparable to wild-type. (J:105554)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cebpa Mutation:  3 strains or lines available
References
Original:  J:105554 Porse BT, et al., The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo. Mol Cell Biol. 2006 Feb;26(3):1028-37
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory