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Tg(Tyr-cre/ERT2)1Lru
Transgene Detail
Nomenclature
Symbol: Tg(Tyr-cre/ERT2)1Lru
Name: transgene insertion 1, Lionel Larue
MGI ID: MGI:3617509
Synonyms: Tg(Tyr-cre/ERT2)1Laru, Tyr::Cre-ERT2
Transgene: Tg(Tyr-cre/ERT2)1Lru  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6 x DBA/2
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    induced by tamoxifen
Mutation:    Insertion
 
Mutation details
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tyr     Summary of all recombinase alleles driven by Tyr.
 

Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Phenotypic Similarity to Human Syndrome: Melanoma (tamoxifen-treated Braftm1Cpri/ Braftm1Cpri Tg(Tyr-cre/ERT2)1Laru mice J:147434)

References
Original:  J:105276 Yajima I, et al., Spatiotemporal gene control by the Cre-ERT2 system in melanocytes. Genesis. 2006 Jan;44(1):34-43
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory