Tg(Ttr-Ercc1)17Dwm
Transgene Detail

Summary

• Symbol: Tg(Ttr-Ercc1)17Dwm
• Name: transgene insertion 17, David W Melton
• MGI ID: MGI:3617449
• Synonyms: TTR/ERCC1
• Transgene: Tg(Ttr-Ercc1)17Dwm Location: unknown
• Alliance: Tg(Ttr-Ercc1)17Dwm page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ttr-Ercc1)17Dwm expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ercc1 (MGI:95412)

• Mutation details: Enhancer and promoter sequences from mouse Ttr drive liver specific expression of a cDNA fragment of mouse Ercc1 containing exons 1-10. (J:106084)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:106084 Selfridge J, et al., Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene. Nucleic Acids Res. 2001 Nov 15;29(22):4541-50
• All: 5 reference(s)