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Rab3btm1Sud
Targeted Allele Detail
Nomenclature
Symbol: Rab3btm1Sud
Name: RAB3B, member RAS oncogene family; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:3615355
Gene: Rab3b  Location: Chr4:108879063-108943324 bp, + strand  Genetic Position: Chr4, 50.67 cM, cytoband C7
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105478
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exon 1, encoding residues 1-76, with a neomycin resistance cassette. Absence of protein was confirmed in immunoblot analysis of mutant brain samples. (J:105478)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rab3b Mutation:  6 strains or lines available
References
Original:  J:105478 Schluter OM, et al., A complete genetic analysis of neuronal Rab3 function. J Neurosci. 2004 Jul 21;24(29):6629-37
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory