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Osr1tm1Jian
Targeted Allele Detail
Nomenclature
Symbol: Osr1tm1Jian
Name: odd-skipped related transcription factor 1; targeted mutation 1, Rulang Jiang
MGI ID: MGI:3613748
Synonyms: Odd1-, Odd1tm1Jian, Odd1tm1RJ
Gene: Osr1  Location: Chr12:9574442-9581500 bp, + strand  Genetic Position: Chr12, 4.05 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104942
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting construct was designed to insert a lacZ-loxP-neo-loxP cassette into exon 2. The cassette replaces 335 bp of the coding region. The expected protein would contain a functional beta-gal fused to the N-terminal 16 amino acids. X-gal staining detected lacZ activity corresponding to expected activity of the endogenous protein. (J:104942)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 66 assay results
In Structures Affected by this Mutation: 20 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Osr1 Mutation:  12 strains or lines available
References
Original:  J:104942 Wang Q, et al., Odd-skipped related 1 (Odd 1) is an essential regulator of heart and urogenital development. Dev Biol. 2005 Dec 15;288(2):582-94
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory