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Arpc3Tn(sb-lacZ,GFP)T5.117Jtak
Transposon induced Allele Detail
Nomenclature
Symbol: Arpc3Tn(sb-lacZ,GFP)T5.117Jtak
Name: actin related protein 2/3 complex, subunit 3; transposon insertion T5.117, Junji Takeda
MGI ID: MGI:3613188
Synonyms: Arpc3Tp
Gene: Arpc3  Location: Chr5:122391878-122406181 bp, + strand  Genetic Position: Chr5, 62.34 cM
Mutation
origin
Strain of Origin:  mixed
Mutation
description
Allele Type:    Transposon induced (Null/knockout, Reporter)
Mutation:    Transposon insertion
 
Mutation detailsTransposition of a single copy of a sleeping beauty transposable element gene trap vector occurred into an exon of this gene disrupting RNA expression as shown by RT-PCR analysis. This gene trap vector consists of the inverted repeat direct repeat sequence specific for sleeping beauty transposase flanking human BCL2 splice acceptor sequence, IRES, LacZ, poly A signal, a chimeric CAG promoter containing sequence from the chicken ACTB promoter, GFP, and splice donor sequence. LacZ expression is seen at E11.5 in specific regions of the embryo including the limb buds and somites. mixed. This allele was generated from mice carrying TgTn(sb-lacZ,GFP)T5Jtak and Tg(ACTB-sb10)1Jtak. (J:104039)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Arpc3 Mutation:  6 strains or lines available
References
Original:  J:104039 Horie K, et al., Characterization of Sleeping Beauty transposition and its application to genetic screening in mice. Mol Cell Biol. 2003 Dec;23(24):9189-207
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory