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TgTn(sb-lTRA-GFP)BJtak
Transgene Detail
Summary
Symbol: TgTn(sb-lTRA-GFP)BJtak
Name: transgenic transposon concatemer B, Junji Takeda
MGI ID: MGI:3613043
Transgene: TgTn(sb-lTRA-GFP)BJtak  Location: unknown  Genetic Position: Chr3, Syntenic
Alliance: TgTn(sb-lTRA-GFP)BJtak page
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic (Transposon concatemer)
Mutation:    Insertion
 
Mutation detailsA concatemer of sleeping beauty transposable elements each consisting of a floxed PGK-neo cassette followed by inverted repeat direct repeat sequence specific for sleeping beauty transposase flanking an ACTB promoter driving GFP expression. Expression of GFP is not seen in the concatemer but is seen after transposition. Transposition by sleeping beauty transposase moves only the ACTB-GFP construct and not the PGK-neo cassette. Integration of the concatemer in this line occurred in chromosome 3. (J:70671)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:70671 Horie K, et al., Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9191-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory