Nkrf^tm1Hjh
Targeted Allele Detail

Summary

• Symbol: Nkrf^tm1Hjh
• Name: NF-kappaB repressing factor; targeted mutation 1, Hansjorg Hauser
• MGI ID: MGI:3612956
• Synonyms: NRF-flox
• Gene: Nkrf Location: ChrX:36151193-36167166 bp, - strand Genetic Position: ChrX, 21.3 cM, cytoband A2
• Alliance: Nkrf^tm1Hjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104192
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The 5' half of the exon 2 was flanked with loxP sites, with the insertion of a stop codon and a neo at the 3' loxP site. Transcript resulting from this locus contains sequence encoding the N-terminal half of the protein and the neo and was detected in Northern blot. (J:104192)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nkrf Mutation: 8 strains or lines available

References

• Original: J:104192 Froese N, et al., Innate Immune Responses in NF-{kappa}B-Repressing Factor-Deficient Mice. Mol Cell Biol. 2006 Jan;26(1):293-302
• All: 1 reference(s)