Agtpbp1^atms
Spontaneous Allele Detail

Summary

• Symbol: Agtpbp1^atms
• Name: ATP/GTP binding protein 1; ataxia and male sterility
• MGI ID: MGI:3612160
• Synonyms: AMS, Nna1^ams
• Gene: Agtpbp1 Location: Chr13:59597348-59705184 bp, - strand
• Alliance: Agtpbp1^atms page

Mutation origin

• Strain of Origin: MRL-Fas^lpr

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Nucleotide substitutions
• Mutation details: A point mutation (G to C) in the 2423rd bp of exon 17 results in the amino acid substitution of proline for arginine at position 808. (J:278981)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agtpbp1 Mutation: 66 strains or lines available

Notes

It is unknown if mice homozygous for Fas^lpr on the MRL/Mp-Fas^lpr atms background are heterozygous or wild-type for atms and if mice homozygous for atms on the MRL/MP-Fas^lpr atms background are heterozygous or wild-type for Fas^lpr (J:103944).

References

• Original: J:103945 Harada T, et al., Ataxia and male sterility (AMS) mouse. A new genetic variant exhibiting degeneration and loss of cerebellar Purkinje cells and spermatic cells. Pathol Int. 2003 Jun;53(6):382-9
• All: 6 reference(s)