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Polqtm1Jcs
Targeted Allele Detail
Nomenclature
Symbol: Polqtm1Jcs
Name: polymerase (DNA directed), theta; targeted mutation 1, John C Schimenti
MGI ID: MGI:3610670
Synonyms: Polq-
Gene: Polq  Location: Chr16:36832148-36915779 bp, + strand  Genetic Position: Chr16, 26.32 cM, cytoband B4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94088
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to insert an in-frame stop codon into exon 1 and replace exons 2-5 with a neomycin resistance gene. (J:94088)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Polq Mutation:  82 strains or lines available
References
Original:  J:94088 Shima N, et al., The Mouse Genomic Instability Mutation chaos1 Is an Allele of Polq That Exhibits Genetic Interaction with Atm. Mol Cell Biol. 2004 Dec;24(23):10381-9
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory