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Mybl2tm1.1Jof
Targeted Allele Detail
Nomenclature
Symbol: Mybl2tm1.1Jof
Name: myeloblastosis oncogene-like 2; targeted mutation 1.1, Jon Frampton
MGI ID: MGI:3610476
Synonyms: B-mybF
Gene: Mybl2  Location: Chr2:163054687-163084688 bp, + strand  Genetic Position: Chr2, 84.0 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:103413
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    The FRT-flanked neo was removed, leaving exons 2-5 flanked with loxP sites. (J:103413)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mybl2 Mutation:  107 strains or lines available
Notes

Phenotypic Similarity to Human Syndrome: Myeloproliferative neoplasm (MPN) J:149060.

References
Original:  J:103413 Garcia P, et al., Generation of a conditional allele of the B-myb gene. Genesis. 2005 Dec;43(4):189-95
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory