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Targeted Allele Detail
Symbol: Ap2m1tm1Ohno
Name: adaptor-related protein complex 2, mu 1 subunit; targeted mutation 1, Hiroshi Ohno
MGI ID: MGI:3608896
Synonyms: mu2-
Gene: Ap2m1  Location: Chr16:20535480-20544909 bp, + strand  Genetic Position: Chr16, 12.46 cM, cytoband 16
Germline Transmission:  Earliest citation of germline transmission: J:102181
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene in reverse orientation replaced exons 3-11. Western blot indicated a decreased amount of protein in heterozygous MEFs. (J:102181)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ap2m1 Mutation:  37 strains or lines available
Original:  J:102181 Mitsunari T, et al., Clathrin adaptor AP-2 is essential for early embryonal development. Mol Cell Biol. 2005 Nov;25(21):9318-23
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory