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Adamts13tm2.1Dgi
Targeted Allele Detail
Nomenclature
Symbol: Adamts13tm2.1Dgi
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13; targeted mutation 2.1, David Ginsburg
MGI ID: MGI:3605826
Synonyms: Adamts13delta ex3
Gene: Adamts13  Location: Chr2:26973416-27009628 bp, + strand  Genetic Position: Chr2, 19.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101752
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Cre mediated recombination was used to remove exon 3. (J:101752)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adamts13 Mutation:  45 strains or lines available
References
Original:  J:101752 Motto DG, et al., Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. J Clin Invest. 2005 Oct;115(10):2752-61
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory