Adamts13tm2.1Dgi
Targeted Allele Detail
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Symbol: |
Adamts13tm2.1Dgi |
Name: |
ADAM metallopeptidase with thrombospondin type 1 motif 13; targeted mutation 2.1, David Ginsburg |
MGI ID: |
MGI:3605826 |
Synonyms: |
Adamts13delta ex3 |
Gene: |
Adamts13 Location: Chr2:26863428-26899640 bp, + strand Genetic Position: Chr2, 19.14 cM
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Alliance: |
Adamts13tm2.1Dgi page
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Germline Transmission: |
Earliest citation of germline transmission:
J:101752
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129X1/Sv
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intragenic deletion
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Cre mediated recombination was used to remove exon 3. (J:101752)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Adamts13 Mutation: |
69 strains or lines available
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Original: |
J:101752 Motto DG, et al., Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. J Clin Invest. 2005 Oct;115(10):2752-61 |
All: |
2 reference(s) |
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