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Vdrtm1Tyam
Targeted Allele Detail
Nomenclature
Symbol: Vdrtm1Tyam
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor; targeted mutation 1, Takeyoshi Yamashita
MGI ID: MGI:3604810
Synonyms: VDR-
Gene: Vdr  Location: Chr15:97854425-97910630 bp, - strand  Genetic Position: Chr15, 53.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101456
Parent Cell Line:  TT2F (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced the 83 bp internal sequence of exon 2. RT-PCR of mutant bone and kidney failed to detect transcript. (J:101456)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vdr Mutation:  17 strains or lines available
References
Original:  J:101456 Shimada T, et al., Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism. Am J Physiol Renal Physiol. 2005 Nov;289(5):F1088-95
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory