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Craddtm1Mak
Targeted Allele Detail
Nomenclature
Symbol: Craddtm1Mak
Name: CASP2 and RIPK1 domain containing adaptor with death domain; targeted mutation 1, Tak W Mak
MGI ID: MGI:3604302
Synonyms: RAIDD-
Gene: Cradd  Location: Chr10:95174746-95324133 bp, - strand  Genetic Position: Chr10, 49.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101402
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin resistance gene. Northern blot confirmed the lack of RNA expression in mutant liver samples. (J:101402)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cradd Mutation:  111 strains or lines available
References
Original:  J:101402 Berube C, et al., Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14314-20
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory