About   Help   FAQ
Sstr5tm1Hawi
Targeted Allele Detail
Nomenclature
Symbol: Sstr5tm1Hawi
Name: somatostatin receptor 5; targeted mutation 1, Hilary A Wilkinson
MGI ID: MGI:3603655
Gene: Sstr5  Location: Chr17:25489875-25497288 bp, - strand  Genetic Position: Chr17, 12.62 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101259
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe single coding exon was replaced with neo and lacZ genes. Expression of lacZ was detected in the brain. RT-PCR confirmed the absence of RNA expression in the pancreas, endocrine islets, brain, and adipose tissue. (J:101259)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sstr5 Mutation:  10 strains or lines available
References
Original:  J:101259 Strowski MZ, et al., Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis. Mol Endocrinol. 2003 Jan;17(1):93-106
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/12/2019
MGI 6.14
The Jackson Laboratory