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Insig1tm1Mbjg
Targeted Allele Detail
Nomenclature
Symbol: Insig1tm1Mbjg
Name: insulin induced gene 1; targeted mutation 1, Joseph L Goldstein
MGI ID: MGI:3603523
Synonyms: Insig1f, Insig1tm1Jlg
Gene: Insig1  Location: Chr5:28071363-28078662 bp, + strand  Genetic Position: Chr5, 13.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101203
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Insig1 Mutation:  2 strains or lines available
References
Original:  J:101203 Engelking LJ, et al., Schoenheimer effect explained - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. J Clin Invest. 2005 Sep;115(9):2489-98
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory