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Avpr1atm1Sbhu
Targeted Allele Detail
Nomenclature
Symbol: Avpr1atm1Sbhu
Name: arginine vasopressin receptor 1A; targeted mutation 1, Shuang-Bao Hu
MGI ID: MGI:3603461
Synonyms: Avpr1a-, Avpr1atm1Ifb, v1a-, V1aRKO
Gene: Avpr1a  Location: Chr10:122448499-122453452 bp, + strand  Genetic Position: Chr10, 70.36 cM, cytoband D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:105892
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.5 kb fragment of the locus starting at 31 bp downstream of the translation start site and ending at 244 bp downstream of exon 1 was replaced by a neomycin resistance cassette. (J:105892)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Avpr1a Mutation:  26 strains or lines available
References
Original:  J:105892 Hu SB, et al., Vasopressin receptor 1a-mediated negative regulation of B cell receptor signaling. J Neuroimmunol. 2003 Feb;135(1-2):72-81
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory