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Acacatm1Sjw
Targeted Allele Detail
Nomenclature
Symbol: Acacatm1Sjw
Name: acetyl-Coenzyme A carboxylase alpha; targeted mutation 1, Salih J Wakil
MGI ID: MGI:3603457
Synonyms: Acc1-, Acc1tm1AL
Gene: Acaca  Location: Chr11:84129672-84401651 bp, + strand  Genetic Position: Chr11, 51.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101150
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsTwo of the exons upstream of the biotin-binding motif were replaced with an HPRT expression cassette. (J:101150)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acaca Mutation:  13 strains or lines available
References
Original:  J:101150 Abu-Elheiga L, et al., Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12011-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory