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Gngt1tm1Yf
Targeted Allele Detail
Nomenclature
Symbol: Gngt1tm1Yf
Name: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; targeted mutation 1, Yoshitaka Fukada
MGI ID: MGI:3603438
Gene: Gngt1  Location: Chr6:3993792-3997436 bp, + strand  Genetic Position: Chr6, 1.81 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101020
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsAn S74L mutation was inserted into exon 4. Immunoblots demonstrated comparable levels of proteins in mutants and wild-type animals. (J:101020)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gngt1 Mutation:  8 strains or lines available
References
Original:  J:101020 Kassai H, et al., Farnesylation of retinal transducin underlies its translocation during light adaptation. Neuron. 2005 Aug 18;47(4):529-39
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory