About   Help   FAQ
Neurod1tm1Kan
Targeted Allele Detail
Nomenclature
Symbol: Neurod1tm1Kan
Name: neurogenic differentiation 1; targeted mutation 1, Klaus-Armin Nave
MGI ID: MGI:3603334
Synonyms: Neurod1f, NeuroDloxP(neoTk)
Gene: Neurod1  Location: Chr2:79452521-79456751 bp, - strand  Genetic Position: Chr2, 47.58 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101098
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo was inserted into intron 1 and a third loxP site was inserted in the 3' UTR. RT-PCR and Northern blot confirmed aberrant splicing of exon 1 to the neo cassette, creating a nonfunctional allele. (J:101098)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neurod1 Mutation:  4 strains or lines available
References
Original:  J:101098 Goebbels S, et al., Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2. Genesis. 2005 Aug;42(4):247-52
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/12/2015
MGI 5.21
The Jackson Laboratory