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Tg(Lck-Cd1d1)1Aben
Transgene Detail
Nomenclature
Symbol: Tg(Lck-Cd1d1)1Aben
Name: transgene insertion 1, Albert Bendelac
MGI ID: MGI:3589763
Synonyms: pLck-CD1d
Transgene: Tg(Lck-Cd1d1)1Aben  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Lck-Cd1d1)1Aben expresses 1 gene
 
Mutation detailsThe Cd1d1 coding sequence was inserted into the second exon of the betaglobin expression cassette and subsequently placed under the control of the proximal Lck promoter. Expression of the Cd1d1 cDNA was demonstrated in the T cell lineage. (J:100545)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
The construct was microinjected into fertilized NOD oocytes as well.
References
Original:  J:100545 Wei DG, et al., Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med. 2005 Jul 18;202(2):239-48
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory