Tg(Lck-Cd1d1)1Aben
Transgene Detail

Summary

• Symbol: Tg(Lck-Cd1d1)1Aben
• Name: transgene insertion 1, Albert Bendelac
• MGI ID: MGI:3589763
• Synonyms: pLck-CD1d
• Transgene: Tg(Lck-Cd1d1)1Aben Location: unknown
• Alliance: Tg(Lck-Cd1d1)1Aben page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Cd1d1)1Aben expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cd1d1 (MGI:107674)

• Mutation details: The Cd1d1 coding sequence was inserted into the second exon of the betaglobin expression cassette and subsequently placed under the control of the proximal Lck promoter. Expression of the Cd1d1 cDNA was demonstrated in the T cell lineage. (J:100545)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

The construct was microinjected into fertilized NOD oocytes as well.

References

• Original: J:100545 Wei DG, et al., Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med. 2005 Jul 18;202(2):239-48
• All: 3 reference(s)