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Cxadrtm1Dvst
Targeted Allele Detail
Nomenclature
Symbol: Cxadrtm1Dvst
Name: coxsackie virus and adenovirus receptor; targeted mutation 1, Dietmar Vestweber
MGI ID: MGI:3587803
Synonyms: CAR-
Gene: Cxadr  Location: Chr16:78301496-78359785 bp, + strand  Genetic Position: Chr16, 45.28 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100174
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exon 1, which contains the ATG start codon. Western blot of embryos failed to detect protein in mutants. (J:100174)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cxadr Mutation:  6 strains or lines available
References
Original:  J:100174 Dorner AA, et al., Coxsackievirus-adenovirus receptor (CAR) is essential for early embryonic cardiac development. J Cell Sci. 2005 Aug 1;118(Pt 15):3509-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory