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Apoa5tm1Hgc
Targeted Allele Detail
Nomenclature
Symbol: Apoa5tm1Hgc
Name: apolipoprotein A-V; targeted mutation 1, Edward M Rubin
MGI ID: MGI:3586505
Synonyms: apoa5
Gene: Apoa5  Location: Chr9:46268633-46271919 bp, + strand  Genetic Position: Chr9, 25.37 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72092
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene replaced the entire locus. Northern blot of mutant mice comfirmed the absence of transcript. (J:72092)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apoa5 Mutation:  3 strains or lines available
References
Original:  J:72092 Pennacchio LA, et al., An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science. 2001 Oct 5;294(5540):169-73
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory