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Targeted Allele Detail
Symbol: Rdh11tm1Akjc
Name: retinol dehydrogenase 11; targeted mutation 1, Anne Kasus-Jacobi
MGI ID: MGI:3586379
Synonyms: rdh11-
Gene: Rdh11  Location: Chr12:79174233-79191855 bp, - strand  Genetic Position: Chr12, 35.51 cM
Germline Transmission:  Earliest citation of germline transmission: J:99913
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsVelicigene technology was used to insert a lacZ-PGK-neo cassette in frame with the first four amino acids. Immunoblot of liver and testis showed absence of protein in mutants. (J:99913)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rdh11 Mutation:  4 strains or lines available
Original:  J:99913 Kasus-Jacobi A, et al., Functional characterization of mouse RDH11 as a retinol dehydrogenase involved in dark adaptation in vivo. J Biol Chem. 2005 May 27;280(21):20413-20
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory