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Transgene Detail
Symbol: Tg(tetO-Vegfa)90Ala
Name: transgene insertion 90, Ann L Akeson
MGI ID: MGI:3586336
Synonyms: (tetO)7VEGF, (tetO)7VEGF164+, tetOVEGF164
Transgene: Tg(tetO-Vegfa)90Ala  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
Mutation detailsThis transgene contains cDNA for the murine Vegfa isoform VEGF-A164 which was inserted between seven copies of the tetracycline Operator (tetO)7-CMV minimal promoter and the bovine growth factor polyadenylation signals sequence. TetO, when present in cells also carrying a tetracycline transactivator (tTA) or reverse transactivator (rtTA) transgene, is inactivated or activated, respectively, by the administration of tetracycline or its analogue doxycycline. (J:86840)
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:86840 Akeson AL, et al., Temporal and spatial regulation of VEGF-A controls vascular patterning in the embryonic lung. Dev Biol. 2003 Dec 15;264(2):443-55
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
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