About   Help   FAQ
Cd8atm1.1Litt
Targeted Allele Detail
Nomenclature
Symbol: Cd8atm1.1Litt
Name: CD8 antigen, alpha chain; targeted mutation 1.1, Dan R Littman
MGI ID: MGI:3584478
Synonyms: E8i delta
Gene: Cd8a  Location: Chr6:71373427-71379173 bp, + strand  Genetic Position: Chr6, 32.14 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:50624
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis allele was derived from Cd8atm1Litt by crossing to mice expressing an unspecified CMV-cre transgene which results in germline excision of the floxed neomycin cassette. (J:50624)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd8a Mutation:  19 strains or lines available
References
Original:  J:50624 Ellmeier W, et al., Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells. Immunity. 1998 Oct;9(4):485-96
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory