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Tg(Th-cre)1Tmd
Transgene Detail
Nomenclature
Symbol: Tg(Th-cre)1Tmd
Name: transgene insertion 1, Ted M Dawson
MGI ID: MGI:3584380
Synonyms: TH-cre
Transgene: Tg(Th-cre)1Tmd  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsCre recombinase is expressed under the control of the rat tyrosine hydroxylase promoter. Cre recombinase activity is detected in catecholaminergic cells. This is a representative record representing TH-cre1 - TH-cre5 all of which have identical activity. The authors state that TH-cre4 appears to be X-linked. (J:99848)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Th     Summary of all recombinase alleles driven by Th.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:99848 Savitt JM, et al., Bcl-x is required for proper development of the mouse substantia nigra. J Neurosci. 2005 Jul 20;25(29):6721-8
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory