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Mcm3aptm1Imku
Targeted Allele Detail
Nomenclature
Symbol: Mcm3aptm1Imku
Name: minichromosome maintenance complex component 3 associated protein; targeted mutation 1, Nobuo Sakaguchi
MGI ID: MGI:3583894
Synonyms: ganp flox
Gene: Mcm3ap  Location: Chr10:76468927-76515857 bp, + strand  Genetic Position: Chr10, 38.88 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:88276
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a neomycin resistance gene downstream of exon 2. LoxP sites were inserted to flank exon 2 and the neo cassette. (J:88276)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mcm3ap Mutation:  54 strains or lines available
References
Original:  J:88276 Kuwahara K, et al., Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1010-5
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory