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Targeted Allele Detail
Symbol: Hus1tm1.1Rsw
Name: HUS1 checkpoint clamp component; targeted mutation 1.1, Robert S Weiss
MGI ID: MGI:3583576
Synonyms: Hus1delta2,3
Gene: Hus1  Location: Chr11:8993137-9011191 bp, - strand  Genetic Position: Chr11, 5.74 cM
Germline Transmission:  Earliest citation of germline transmission: J:99339
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsHus1tm1Rsw mice were crossed with mice expressing cre in the germline, resulting in the excision of exons 2 and 3. Sequencing of RT-PCR products from mutants confirmed the lack of exons 2 and 3 as well as the first three nucleotides of exon 4. (J:99339)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hus1 Mutation:  14 strains or lines available
Original:  J:99339 Levitt PS, et al., Conditional inactivation of the mouse Hus1 cell cycle checkpoint gene. Genomics. 2005 Aug;86(2):212-24
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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