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Cd207tm2Mal
Targeted Allele Detail
Nomenclature
Symbol: Cd207tm2Mal
Name: CD207 antigen; targeted mutation 1, Bernard Malissen
MGI ID: MGI:3581825
Synonyms: Lang-EGFP, muLangerin-EGFP
Gene: Cd207  Location: Chr6:83671215-83677857 bp, - strand  Genetic Position: Chr6, 35.94 cM, cytoband D1-D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99114
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsA vector containing an IRES-EGFP was inserted in the 3' UTR with a Cre-neo auto-deleter cassette, which directs its own excision as it passes through the male germ line. (J:99114)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cd207 Mutation:  17 strains or lines available
References
Original:  J:99114 Kissenpfennig A, et al., Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity. 2005 May;22(5):643-54
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory