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Tg(Tyr-cre)3Gfk
Transgene Detail
Summary
Symbol: Tg(Tyr-cre)3Gfk
Name: transgene insertion 3, Graham F Kay
MGI ID: MGI:3580525
Synonyms: TEC3, TgN(TyrCre)3Gfk
Transgene: Tg(Tyr-cre)3Gfk  Location: unknown  
Alliance: Tg(Tyr-cre)3Gfk page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F2 or (C57BL/6 x 129)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThese transgenes express cre under the control of the tyrosinase promoter. Three lines were reported. Lines 1 and 2 include the full enhancer in addition to the promoter. Line 3 lacks the enhancer. Line 3 expresses cre solely in melanoblasts. (J:87271)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tyr (species not specified)
Summary of all recombinase alleles driven by Tyr.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Tyr-cre)3Gfk
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Strain of origin for these mtransgenes is either BCBF2 or B6129F2. They were subsequently backcrossed to C57BL/6 for maintainance.
References
Original:  J:87271 Tonks ID, et al., Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues. Genesis. 2003 Nov;37(3):131-8
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/26/2022
MGI 6.22
The Jackson Laboratory