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Krasb
Allele Detail
Nomenclature
Symbol: Krasb
Name: Kirsten rat sarcoma viral oncogene homolog; b variant
MGI ID: MGI:3579273
Synonyms: 0.70-kB KRAS2 allele, Allele 2, resistant allele
Gene: Kras  Location: Chr6:145162425-145195965 bp, - strand  Genetic Position: Chr6, 77.37 cM, cytoband G2
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Not Applicable
Mutation:    Undefined
    This variant results in an EcoRI band of 0.7 kb.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kras Mutation:  55 strains or lines available
Notes
The b variant has been observed in the following strains: AKR/J, B10.O20, C58/J, C57BL/6J, C57L/J, C3H/HeJ, OcB6, OcB15 SJL/J and DBA/2J. This variant has been shown to confer resistance to pulmonary tumors.
References
Original:  J:8509 Ryan J, et al., An EcoRI restriction fragment length polymorphism at the KRAS2 locus on mouse chromosome 6. Nucleic Acids Res. 1986 Nov 25;14(22):9222
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory