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Nr2f2tm2.1Tsa
Targeted Allele Detail
Summary
Symbol: Nr2f2tm2.1Tsa
Name: nuclear receptor subfamily 2, group F, member 2; targeted mutation 2.1, Sophia Y Tsai
MGI ID: MGI:3579117
Synonyms: COUP-TFIIflox
Gene: Nr2f2  Location: Chr7:70001692-70016483 bp, - strand  Genetic Position: Chr7, 38.66 cM
Alliance: Nr2f2tm2.1Tsa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98520
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsExons 1-3 remained flanked by loxP sites as cre expression resulted in the excision of a neo at the 3' end of the locus. A lacZ remained downstream of the floxed exons. (J:98520)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 17 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr2f2 Mutation:  27 strains or lines available
References
Original:  J:98520 Takamoto N, et al., COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May;132(9):2179-89
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory