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Dnajc3tm8663Wcl
Targeted Allele Detail
Nomenclature
Symbol: Dnajc3tm8663Wcl
Name: DnaJ heat shock protein family (Hsp40) member C3; targeted mutation 8663, Warren C Ladiges
MGI ID: MGI:3578105
Synonyms: Dnajc3tm1Wcl, P58-, P58IPK, P58IPK-
Gene: Dnajc3  Location: Chr14:118937976-118981697 bp, + strand  Genetic Position: Chr14, 62.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98194
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    An eGFP-betageo cassette replaced exon 1. Protein was absent in Western blot of mutant MEFs. (J:98194)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dnajc3 Mutation:  6 strains or lines available
References
Original:  J:98194 Ladiges WC, et al., Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK. Diabetes. 2005 Apr;54(4):1074-81
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory