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Spi1tm1.3Nutt
Targeted Allele Detail
Nomenclature
Symbol: Spi1tm1.3Nutt
Name: spleen focus forming virus (SFFV) proviral integration oncogene; targeted mutation 1.3, Stephen L Nutt
MGI ID: MGI:3578012
Synonyms: PU.1delta
Gene: Spi1  Location: Chr2:91082390-91115756 bp, + strand  Genetic Position: Chr2, 50.44 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98188
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5 was deleted upon crossing Sfpi1tm1.2Nutt mice with mice expressing cre in the germline. (J:98188)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spi1 Mutation:  12 strains or lines available
References
Original:  J:98188 Dakic A, et al., PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J Exp Med. 2005 May 2;201(9):1487-502
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory