About   Help   FAQ
Abca1tm1.1Jp
Targeted Allele Detail
Nomenclature
Symbol: Abca1tm1.1Jp
Name: ATP-binding cassette, sub-family A (ABC1), member 1; targeted mutation 1.1, John S Parks
MGI ID: MGI:3577725
Synonyms: Abca1-
Gene: Abca1  Location: Chr4:53030787-53159895 bp, - strand  Genetic Position: Chr4, 28.57 cM, cytoband A5-B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98093
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Abca1tm1Jp mice were crossed with Tg(EIIa-cre)C5379Lmgd mice to remove exons 45 and 46. (J:98093)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abca1 Mutation:  9 strains or lines available
References
Original:  J:98093 Timmins JM, et al., Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest. 2005 May 2;115(5):1333-1342
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory