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Targeted Allele Detail
Symbol: Nfkbiatm1.1Kbp
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; targeted mutation 1, Klaus Pfeffer
MGI ID: MGI:3577710
Synonyms: ikbadelta
Gene: Nfkbia  Location: Chr12:55489410-55492647 bp, - strand  Genetic Position: Chr12, 24.0 cM, cytoband C1-C3
Germline Transmission:  Earliest citation of germline transmission: J:97945
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsNfkbiatm1Kbp mice were crossed with cre-expressing mice to remove the promoter region and first two exons in the germ line. All transcripts were lost in tissues analyzed by RT-PCR. (J:97945)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nfkbia Mutation:  10 strains or lines available
Original:  J:97945 Rupec RA, et al., Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity. 2005 Apr;22(4):479-91
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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