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Nfkbiatm1Kbp
Targeted Allele Detail
Summary
Symbol: Nfkbiatm1Kbp
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; targeted mutation 1, Klaus Pfeffer
MGI ID: MGI:3577709
Synonyms: ikbaf
Gene: Nfkbia  Location: Chr12:55536195-55539432 bp, - strand  Genetic Position: Chr12, 24.0 cM, cytoband C1-C3
Alliance: Nfkbiatm1Kbp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97945
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted to flank the promoter region and the first two exons. (J:97945)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nfkbia Mutation:  19 strains or lines available
References
Original:  J:97945 Rupec RA, et al., Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity. 2005 Apr;22(4):479-91
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory