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Il16tm1Korn
Targeted Allele Detail
Nomenclature
Symbol: Il16tm1Korn
Name: interleukin 16; targeted mutation 1, Hardy Kornfeld
MGI ID: MGI:3576925
Synonyms: IL-16-
Gene: Il16  Location: Chr7:83642825-83745726 bp, - strand  Genetic Position: Chr7, 47.43 cM, cytoband D2-D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97739
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding sequence for the mature protein, all of exon 6 and protions of exons 5 and 7, were replaced with a neomycin resistance gene in reverse orientation. The prodomain was left intact. (J:97739)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il16 Mutation:  21 strains or lines available
References
Original:  J:97739 Ren F, et al., Pro-IL-16 regulation in activated murine CD4+ lymphocytes. J Immunol. 2005 Mar 1;174(5):2738-45
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory