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Gt(ROSA)26Sortm1(Smo/EYFP)Amc
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm1(Smo/EYFP)Amc
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Andrew P McMahon
MGI ID: MGI:3576373
Synonyms: Gt(ROSA)26Sortm1(smo/YFP)Amc, R26-lsl-SmoM2, R26SmoM2, R26SmoM2, RosaSmoM2 c, SmoM2, SmoM2fl, SmoM2/Yfp, SmoM2-YFPfl, SmoOEX
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89445
Parent Cell Line:  AV3 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, Constitutively active, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  240 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Medullablastoma (J:139574)

References
Original:  J:89445 Jeong J, et al., Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 2004 Apr 15;18(8):937-51
All:  56 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory