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Transgene Detail
Symbol: Tg(Acr-EGFP)1Osb
Name: transgene insertion 1, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:3575110
Synonyms: Acr3-EGFP, Tg(acro3-EGFP)01Osb, Tg(NCAG-EGFP)CZ-001-FM260Osb
Transgene: Tg(Acr-EGFP)1Osb  Location: unknown  
Strain of Origin:  (C57BL/6 x C3H)F1
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsTransgenic mice were made with a series of constructs in which the acrosin promoter and varying lengths of coding sequence were fused to the EGFP gene. The transgenic line entered here includes the Acr promoter, signal peptide, and N-terminal peptide. This is one of six such lines. Another construct fused only the Acr promoter to EGFP (3 lines). The third construct was made up of the Acr promoter, and signal peptide fused to EGFP (4 lines). The fourth construct was made up of the Acr promoter, signal peptide and a mutated N-terminal peptide in which there is an N to Q substitution (6 lines). (J:97291)
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Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:97291 Nakanishi T, et al., Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein. FEBS Lett. 1999 Apr 23;449(2-3):277-83
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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