About   Help   FAQ
Due to maintenance, access to MGI may be intermittent 8:00 AM ET Wed, September 18.
Targeted Allele Detail
Symbol: Hoxc8tm1Dll
Name: homeobox C8; targeted mutation 1, Jean-Marie Garnier
MGI ID: MGI:3574938
Gene: Hoxc8  Location: Chr15:102990607-102994111 bp, + strand  Genetic Position: Chr15, 58.05 cM
Germline Transmission:  Earliest citation of germline transmission: J:97213
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsThe insertion of a GFP-Aequorin reporter (G5A) resulted in the deletion of codons 2-42 in the coding region. (J:97213)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxc8 Mutation:  0 strains or lines available
Original:  J:97213 Vermot J, et al., Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons. Development. 2005 Apr;132(7):1611-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory