About   Help   FAQ
Spry1tm1Jdli
Targeted Allele Detail
Nomenclature
Symbol: Spry1tm1Jdli
Name: sprouty homolog 1 (Drosophila); targeted mutation 1, Jonathan D Licht
MGI ID: MGI:3574403
Synonyms: Spryflox
Gene: Spry1  Location: Chr3:37639947-37644598 bp, + strand  Genetic Position: Chr3, 18.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96485
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    All three exons, including exon 3 that contains the ORF, was flanked with loxP sites. (J:96485)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Spry1 Mutation:  6 strains or lines available
References
Original:  J:96485 Basson MA, et al., Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell. 2005 Feb;8(2):229-39
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory