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Pax3tm1(cre)Joe
Targeted Allele Detail
Nomenclature
Symbol: Pax3tm1(cre)Joe
Name: paired box 3; targeted mutation 1, Jonathan A Epstein
MGI ID: MGI:3573783
Synonyms: Pax3Cre, Pax3-Cre, Pax3Cre-KI
Gene: Pax3  Location: Chr1:78101267-78197134 bp, - strand  Genetic Position: Chr1, 39.79 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96431
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsA targeting vector was desinged to insert the cre recombinase cDNA followed by a stop codon and a polyA signal in place of exon 1 of the endogenous locus. (J:96431, J:98272)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pax3     Summary of all recombinase alleles driven by Pax3. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 93 assay results
In Structures Affected by this Mutation: 14 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax3 Mutation:  21 strains or lines available
References
Original:  J:96431 Lang D, et al., Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature. 2005 Feb 24;433(7028):884-7
All:  98 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory