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Spink5tm1Hov
Targeted Allele Detail
Nomenclature
Symbol: Spink5tm1Hov
Name: serine peptidase inhibitor, Kazal type 5; targeted mutation 1, Alain Hovnanian
MGI ID: MGI:3573756
Synonyms: Spink5-
Gene: Spink5  Location: Chr18:43963235-44022501 bp, + strand  Genetic Position: Chr18, 23.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96435
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spink5 Mutation:  1 strain or line available
References
Original:  J:96435 Descargues P, et al., Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity. Nat Genet. 2005 Jan;37(1):56-65
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory